Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestifer
The type IX secretion system (T9SS) is specific to the Fibrobacteres-Chlorobi-Bacteroidetes superphylum, the members of which have many specialized features, including gliding motility and the transport of cargo proteins across the outer membrane. At least 20 proteins have been identified as the com...
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| Language: | English |
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Elsevier
2025-01-01
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| Series: | Current Research in Microbial Sciences |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666517425000665 |
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| author | Pengfei Niu Rong Guo Chan Ding Shengqing Yu |
| author_facet | Pengfei Niu Rong Guo Chan Ding Shengqing Yu |
| author_sort | Pengfei Niu |
| collection | DOAJ |
| description | The type IX secretion system (T9SS) is specific to the Fibrobacteres-Chlorobi-Bacteroidetes superphylum, the members of which have many specialized features, including gliding motility and the transport of cargo proteins across the outer membrane. At least 20 proteins have been identified as the components of T9SS. Proteins secreted by T9SS use the Sec system to cross the inner membrane, and the conserved C-terminal domain targets them to the T9SS for delivery to the extracellular environment or attachment to the outer membrane. Riemerella anatipestifer is an important pathogen of waterfowl, causing septicemic and exudative diseases. A genetic analysis recently detected T9SS in R. anatipestifer, in which it transports proteins and affects virulence. Moreover, at least 19 T9SS-transported proteins in R. anatipestifer strain Yb2 were identified, with multiple functions and affecting R. anatipestifer in different ways. In this review, we focus on recent advances in our understanding of the structure, function, and organization of the T9SS machinery and new findings about this highly novel secretion system in R. anatipestifer. |
| format | Article |
| id | doaj-art-92c69e8b37fb46d99b3b30f097f47f83 |
| institution | Kabale University |
| issn | 2666-5174 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Current Research in Microbial Sciences |
| spelling | doaj-art-92c69e8b37fb46d99b3b30f097f47f832025-08-26T04:14:34ZengElsevierCurrent Research in Microbial Sciences2666-51742025-01-01910040410.1016/j.crmicr.2025.100404Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestiferPengfei Niu0Rong Guo1Chan Ding2Shengqing Yu3Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Shanghai, 200241, PR China; Jiangsu Agri-Animal Husbandry Vocational College, Veterinary Bio-Pharmaceutical, Jiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Taizhou, 225309, PR China; Fujian Agriculture and Forestry University, Fuzhou, 350002, PR ChinaJiangsu Agri-Animal Husbandry Vocational College, Veterinary Bio-Pharmaceutical, Jiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Taizhou, 225309, PR ChinaShanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Shanghai, 200241, PR China; Corresponding authors at: Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Shanghai, 200241, PR China.Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Shanghai, 200241, PR China; Jiangsu Agri-Animal Husbandry Vocational College, Veterinary Bio-Pharmaceutical, Jiangsu Key Laboratory for High-Tech Research and Development of Veterinary Biopharmaceuticals, Taizhou, 225309, PR China; Fujian Agriculture and Forestry University, Fuzhou, 350002, PR China; Corresponding authors at: Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Shanghai, 200241, PR China.The type IX secretion system (T9SS) is specific to the Fibrobacteres-Chlorobi-Bacteroidetes superphylum, the members of which have many specialized features, including gliding motility and the transport of cargo proteins across the outer membrane. At least 20 proteins have been identified as the components of T9SS. Proteins secreted by T9SS use the Sec system to cross the inner membrane, and the conserved C-terminal domain targets them to the T9SS for delivery to the extracellular environment or attachment to the outer membrane. Riemerella anatipestifer is an important pathogen of waterfowl, causing septicemic and exudative diseases. A genetic analysis recently detected T9SS in R. anatipestifer, in which it transports proteins and affects virulence. Moreover, at least 19 T9SS-transported proteins in R. anatipestifer strain Yb2 were identified, with multiple functions and affecting R. anatipestifer in different ways. In this review, we focus on recent advances in our understanding of the structure, function, and organization of the T9SS machinery and new findings about this highly novel secretion system in R. anatipestifer.http://www.sciencedirect.com/science/article/pii/S2666517425000665Type IX secretion systemFibrobacteres–Chlorobi–Bacteroidetes superphylumSecretion systemRiemerella anatipestiferVirulence |
| spellingShingle | Pengfei Niu Rong Guo Chan Ding Shengqing Yu Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestifer Current Research in Microbial Sciences Type IX secretion system Fibrobacteres–Chlorobi–Bacteroidetes superphylum Secretion system Riemerella anatipestifer Virulence |
| title | Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestifer |
| title_full | Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestifer |
| title_fullStr | Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestifer |
| title_full_unstemmed | Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestifer |
| title_short | Advances in the type IX secretion system: an exploration focusing on Riemerella anatipestifer |
| title_sort | advances in the type ix secretion system an exploration focusing on riemerella anatipestifer |
| topic | Type IX secretion system Fibrobacteres–Chlorobi–Bacteroidetes superphylum Secretion system Riemerella anatipestifer Virulence |
| url | http://www.sciencedirect.com/science/article/pii/S2666517425000665 |
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