Validation of a data-driven multicomponent T2 analysis for quantifying myelin content in the cuprizone mouse model of multiple sclerosis.

Validation of a data-driven multicomponent T2 analysis for quantifying myelin content in the cuprizone mouse model of multiple sclerosis.

<h4>Background</h4>Myelin quantification is essential for understanding a wide range of neurodegenerative pathologies. Voxel-wise multicomponent T2 (mcT2) analysis is the common approach for this purpose, yet no gold standard technique exist that can overcome the ambiguity of fitting sev...

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Main Authors: Noam Omer, Ella Wilczynski, Sharon Zlotzover, Coral Helft, Tamar Blumenfeld-Katzir, Noam Ben-Eliezer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0323614
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