Virtual Clinical Trial Reveals Significant Clinical Potential of Targeting Tumor‐Associated Macrophages and Microglia to Treat Glioblastoma

ABSTRACT Glioblastoma is the most aggressive primary brain tumor, with a median survival of 15 months with treatment. Standard‐of‐care (SOC) consists of resection, radio‐ and chemotherapy. Clinical trials involving PD‐1 inhibition with nivolumab combined with SOC failed to increase survival. A quant...

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Bibliographic Details
Main Authors: Blanche Mongeon, Morgan Craig
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Subjects:
Online Access:https://doi.org/10.1002/psp4.70033
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