Profiling of proteases involved in SARS-CoV-2 pathogenesis in human saliva: Influence of age and gender

Background: SARS-CoV-2 enters human cells via angiotensin-converting enzyme 2 (ACE2). In silico experiments also demonstrated possible SARS-CoV-2 binding to dipeptidyl peptidase 4 (DPP-4) during cell entry. Moreover, matrix metalloproteinase 2 (MMP-2) is involved in the SARS-CoV-2 cell fusion proces...

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Bibliographic Details
Main Authors: Mentalla Motaz Abdellatif, Azza El Amir, Said Shalaby, Michael Kirschfink, Rola Nadeem, Dina Nadeem Abd-Elshafy, Mahmoud Mohamed Bahgat
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Journal of Genetic Engineering and Biotechnology
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Online Access:http://www.sciencedirect.com/science/article/pii/S1687157X25000538
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