SPISE INDEX (Single point insulin sensitivity estimator): indicator of insulin resistance in children and adolescents with overweight and obesity

SPISE INDEX (Single point insulin sensitivity estimator): indicator of insulin resistance in children and adolescents with overweight and obesity

BackgroundInsulin resistance in children and adolescents with obesity is linked to increased risk of type 2 diabetes mellitus and cardiovascular disease. The SPISE index, based on values of fasting triglycerides (mg/dL), HDL cholesterol (mg/dL), and BMI (kg/m2), shows promise in predicting insulin r...

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Main Authors: Giacomo Tantari, Marta Bassi, Angela Pistorio, Nicola Minuto, Flavia Napoli, Gianluca Piccolo, Alberto La Valle, Giordano Spacco, Carla Cervello, Giuseppe D’Annunzio, Mohamad Maghnie
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Endocrinology
Subjects:
obesity
overweight
insulin resistance
type 2 diabetes mellitus
adolescence
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1439901/full
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https://www.frontiersin.org/articles/10.3389/fendo.2024.1439901/full

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