МODIFIED CROSS-LINKING IN THE TRЕATMENT OF ADVANCED PURULENT CORNEAL ULCER. СLINICAL CASE
Purpose: To describe the clinical case of advanced purulent corneal ulcer successfully treated with modified cross-linking (M-CXL). Key points: A developed purulent corneal ulcer augmenting from the center to the limb with stromal lysis in the zone of keratotomy incisions gradually progressed despit...
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| Format: | Article |
| Language: | Russian |
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Ophthalmology Publishing Group
2017-10-01
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| Series: | Oftalʹmologiâ |
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| Online Access: | https://www.ophthalmojournal.com/opht/article/view/401 |
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| author | Evg. A. Kasparova Ian Byao O. I. Sobkova |
| author_facet | Evg. A. Kasparova Ian Byao O. I. Sobkova |
| author_sort | Evg. A. Kasparova |
| collection | DOAJ |
| description | Purpose: To describe the clinical case of advanced purulent corneal ulcer successfully treated with modified cross-linking (M-CXL). Key points: A developed purulent corneal ulcer augmenting from the center to the limb with stromal lysis in the zone of keratotomy incisions gradually progressed despite active conservative treatment during 1 month. After 2 sessions of modified PACK-CXL performed with simultaneous frequent instillations of preservant-free moxifloxacin eye drops, the purulent process and corneal lysis was successfully stopped. It allowed to perform optical penetrating keratoplasty in the non-inflamed eye and use smaller graft diameter. Conclusion: M-CRL demonstrated an excellent therapeutic effect — rapid resorption of active purulent infiltration and suppression of purulent corneal melting. This allowed to avoid emergency keratoplasty and to conduct it as a planned operation. M-CXL can become a promising method of treating purulent corneal ulcers in the absence of the effect of drug therapy, and also be used as a preparation for keratoplasty surgery to reduce the severity of inflammation and the risk of infection recurrence in the postoperative period. |
| format | Article |
| id | doaj-art-91cd2f686e524f9da5b92b1e526b95e5 |
| institution | Kabale University |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| publishDate | 2017-10-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj-art-91cd2f686e524f9da5b92b1e526b95e52025-08-20T04:00:20ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452017-10-0114327427710.18008/1816-5095-2017-3-274-277359МODIFIED CROSS-LINKING IN THE TRЕATMENT OF ADVANCED PURULENT CORNEAL ULCER. СLINICAL CASEEvg. A. Kasparova0Ian Byao1O. I. Sobkova2Research Institute of Eye DiseasesResearch Institute of Eye DiseasesResearch Institute of Eye DiseasesPurpose: To describe the clinical case of advanced purulent corneal ulcer successfully treated with modified cross-linking (M-CXL). Key points: A developed purulent corneal ulcer augmenting from the center to the limb with stromal lysis in the zone of keratotomy incisions gradually progressed despite active conservative treatment during 1 month. After 2 sessions of modified PACK-CXL performed with simultaneous frequent instillations of preservant-free moxifloxacin eye drops, the purulent process and corneal lysis was successfully stopped. It allowed to perform optical penetrating keratoplasty in the non-inflamed eye and use smaller graft diameter. Conclusion: M-CRL demonstrated an excellent therapeutic effect — rapid resorption of active purulent infiltration and suppression of purulent corneal melting. This allowed to avoid emergency keratoplasty and to conduct it as a planned operation. M-CXL can become a promising method of treating purulent corneal ulcers in the absence of the effect of drug therapy, and also be used as a preparation for keratoplasty surgery to reduce the severity of inflammation and the risk of infection recurrence in the postoperative period.https://www.ophthalmojournal.com/opht/article/view/401pack-crosslinkingmodified crosslinkingfrequent antibiotic eye drops instillationspurulent keratitispurulent corneal ulcerkeratotomy incisionspenetrating keratoplasty |
| spellingShingle | Evg. A. Kasparova Ian Byao O. I. Sobkova МODIFIED CROSS-LINKING IN THE TRЕATMENT OF ADVANCED PURULENT CORNEAL ULCER. СLINICAL CASE Oftalʹmologiâ pack-crosslinking modified crosslinking frequent antibiotic eye drops instillations purulent keratitis purulent corneal ulcer keratotomy incisions penetrating keratoplasty |
| title | МODIFIED CROSS-LINKING IN THE TRЕATMENT OF ADVANCED PURULENT CORNEAL ULCER. СLINICAL CASE |
| title_full | МODIFIED CROSS-LINKING IN THE TRЕATMENT OF ADVANCED PURULENT CORNEAL ULCER. СLINICAL CASE |
| title_fullStr | МODIFIED CROSS-LINKING IN THE TRЕATMENT OF ADVANCED PURULENT CORNEAL ULCER. СLINICAL CASE |
| title_full_unstemmed | МODIFIED CROSS-LINKING IN THE TRЕATMENT OF ADVANCED PURULENT CORNEAL ULCER. СLINICAL CASE |
| title_short | МODIFIED CROSS-LINKING IN THE TRЕATMENT OF ADVANCED PURULENT CORNEAL ULCER. СLINICAL CASE |
| title_sort | мodified cross linking in the trеatment of advanced purulent corneal ulcer сlinical case |
| topic | pack-crosslinking modified crosslinking frequent antibiotic eye drops instillations purulent keratitis purulent corneal ulcer keratotomy incisions penetrating keratoplasty |
| url | https://www.ophthalmojournal.com/opht/article/view/401 |
| work_keys_str_mv | AT evgakasparova modifiedcrosslinkinginthetreatmentofadvancedpurulentcornealulcerslinicalcase AT ianbyao modifiedcrosslinkinginthetreatmentofadvancedpurulentcornealulcerslinicalcase AT oisobkova modifiedcrosslinkinginthetreatmentofadvancedpurulentcornealulcerslinicalcase |