Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location

Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location

Abstract The location of a patient’s colorectal cancer (CRC) influences their outcome but inherited factors may also be involved. We studied 1899 patients with advanced CRC (514 had proximal colonic, 493 distal colonic and 892 rectal tumours) and carried out genome-wide association studies for survi...

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Bibliographic Details
Main Authors: Christopher Wills, Katie Watts, Amy Houseman, Timothy S. Maughan, David Fisher, Nada A. Al-Tassan, Richard S. Houlston, Valentina Escott-Price, Jeremy P. Cheadle
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Colorectal cancer
Survival
Tumour location
Germline variation
Online Access:https://doi.org/10.1038/s41598-024-77870-0
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