A biomathematical model of SARS-CoV-2 in Syrian hamsters

A biomathematical model of SARS-CoV-2 in Syrian hamsters

Abstract When infected with SARS-CoV-2, Syrian hamsters (Mesocricetus auratus) develop moderate disease severity presenting key features of human COVID-19. We here develop a biomathematical model of the disease course by translating known biological mechanisms of virus-host interactions and immune r...

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Bibliographic Details
Main Authors: Sibylle Schirm, Geraldine Nouailles, Holger Kirsten, Jakob Trimpert, Emanuel Wyler, Luiz Gustavo Teixeira Alves, Markus Landthaler, Peter Ahnert, Norbert Suttorp, Martin Witzenrath, Markus Scholz
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
SARS-CoV-2
Mathematical model
Immune response
T-cells
Macrophages
Natural killer cells
Online Access:https://doi.org/10.1038/s41598-024-80498-9
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https://doi.org/10.1038/s41598-024-80498-9

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