Acute and sub-acute toxicity of ethanol extracts of Hagenia abyssinica and Rumex abyssinicus flowers in Swiss albino mice.

Acute and sub-acute toxicity of ethanol extracts of Hagenia abyssinica and Rumex abyssinicus flowers in Swiss albino mice.

<h4>Background</h4>Hagenia abyssinica (Bruce) J.F. Gmel (Family: Rosaceae) and Rumex abyssinicus Jacq (Family: Polygonaceae) are valuable medicinal plants traditionally used in Ethiopia to treat various diseases. Recent studies have also demonstrated that solvent extracts of these plants...

Full description

Saved in:

Bibliographic Details
Main Authors:	Hirut Basha Gemeda, Asfaw Debella, Milkyas Endale, Abiy Abebe, Meharu Mathewos, Wossene Habtu, Dinkenesh Chalchisa, Betelhem Getachew, Menal Hassen, Hassen Mamo
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2025-01-01
Series:	PLoS ONE
Online Access:	https://doi.org/10.1371/journal.pone.0319464
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Molluscicidal Activity of Extracts and Fractions From Hagenia abyssinica, Rosa abyssinica, and Cucumis ficifolius Against Biomphalaria and Bulinus Snails
by: Hirut Basha, et al.
Published: (2024-01-01)

Ethnobotany, phytochemistry, pharmacology and toxicity of Hagenia abyssinica (Bruce) J.F.Gmel.: a review
by: Guohui Shi, et al.
Published: (2025-06-01)

Biogenic Synthesis, Optimization, and characterization of zinc oxide nanoparticles using Rumex abyssinicus Jacq root extract for antioxidant and antibacterial activities
by: Amogne Wendu Digisu, et al.
Published: (2024-12-01)

Review on nutritional properties, health benefits, food industry applications, post-harvest management, and potential risks of Hagenia abyssinica (African Redwood)
by: Desye Alemu Teferi, et al.
Published: (2025-06-01)

In Vitro Antibacterial Activity, Molecular Docking, and ADMET Analysis of Phytochemicals from Roots of <i>Dovyalis abyssinica</i>
by: Dereilo Bekere Belitibo, et al.
Published: (2024-11-01)

In vitro antimicrobial and cytotoxic evaluation of leaf, root, and stem extracts of Solanum dasyphyllum and root and stem extracts of Dovyalis abyssinica
by: Dereilo Bekere Belitibo, et al.
Published: (2025-06-01)

Rumex and Polygonum in Colombia Rumex and Polygonum in Colombia
by: Fassett Norman C.
Published: (1946-12-01)

Comparative evaluation of biometrical and biochemical characteristics of three Rumex representatives: <i>Rumex acetosa</i> L., <i>Rumex sanguineus</i> L. and <i>Rumex confertus</i> Willd.
by: V. A. Kharchenko, et al.
Published: (2023-12-01)

Antioxidant activity and acute toxicity of ziziphus abyssinica extracts: A comparative study of root and leaf extracts
by: Tsegay Beyene Weldemariam, et al.
Published: (2025-12-01)

The value of the crop ‘Crambe abyssinica’ (Crambe Abyssinica) and its productivity in various countries of the world (review)
by: Е. L. Turina, et al.
Published: (2021-09-01)

Ethnobotanical Usages of the Turkish Rumex Taxa
by: Fatma Sarı, et al.
Published: (2021-09-01)

Sorrel, Garden—Rumex acetosa L.
by: James M. Stephens
Published: (2003-05-01)

Neurotropic Viruses as Acute and Insidious Drivers of Aging
by: Angela Rocchi, et al.
Published: (2025-04-01)

Antibacterial Activity of Coumarins and Carbazole Alkaloid from Roots of Clausena anisata
by: Dandena Tamene, et al.
Published: (2019-01-01)

Ecological Implications of Germination Temperature on Native and Invasive Rumex Spp.
by: Michaela Jungová, et al.
Published: (2025-04-01)

Protective Effect and Mechanism of Edible Grass (Rumex patientia L. × Rumex tianschanicus A.LOS) Jiaosu on Alcohol-Induced Injury in HepG2 Cells
by: LI Xianxiu, HE Tao, MAO Yangchen, MAO Jianwei, LAI Xiaojin, SHAO Yihuai, SHA Ruyi
Published: (2025-07-01)

Determination of antioxidant properties of Rumex crispus and Scrophularia canina subsp. bicolor
by: Serhat Demir, et al.
Published: (2017-11-01)

Phytochemical Composition, Antioxidant, Antiacetylcholinesterase, and Cytotoxic Activities of Rumex crispus L.
by: Mohamed Marouane Saoudi, et al.
Published: (2021-01-01)

Antibacterial Activity of Two Flavans from the Stem Bark of Embelia schimperi
by: Babe Guyasa, et al.
Published: (2018-01-01)

PHYTOCHEMICAL SCREENING, IN VITRO ANTIOXIDANT AND ANTIBACTERIAL ACTIVITY OF RUMEX VESICARIUS L. EXTRACT
by: Salah E. Laouini, et al.
Published: (2017-12-01)

The use of Crambe abyssinica seeds as adsorbent in the removal of metals from waters Uso de sementes de Crambe abyssinica como adsorvente na remoção de metais de águas
by: Affonso C. Gonçalves Jr., et al.
Published: (2013-03-01)

Effect of Pretreatment and Drying Methods on the Quality of Anchote (Coccinia abyssinica (Lam.)) Flour
by: Abebe Desalegn, et al.
Published: (2021-01-01)

Phytotoxicity of exotic species on the physiological potential of crambe seeds (Crambe abyssinica Hochs)
by: Silvana Fraga Silva, et al.
Published: (2017-12-01)

Pain-Relieving Property of Artemisia abyssinica and Lepidium sativum (Essential Oil) in Mice
by: Kassahun Dires Ayenew, et al.
Published: (2025-01-01)

Optimization of Bio-Based Adhesive Synthesis From Gelatin and Euphorbia abyssinica Latex
by: Lioul Getachew Alemu, et al.
Published: (2025-01-01)

Phytochemical Analysis of the Aerial Part of Golden Dock (<i>Rumex Maritimus</i> L.)
by: V. V. Podgurskaya, et al.
Published: (2023-05-01)

Antioxidant and cytotoxic activities of curly dock (Rumex crispus L., Polygonaceae) fruit extract
by: Ćebović Tatjana, et al.
Published: (2020-01-01)

Effect of Anchote (Coccinia abyssinica) and Potato Starch Addition on Colloidal Stability of Pineapple Juice
by: Abebaw Teshome Tiruneh, et al.
Published: (2021-01-01)

Effect of Salinity and Nitrogen on Heavy Metal Tolerance and Accumulation Potential in <i>Rumex maritimus</i>
by: Lāsma Neiceniece, et al.
Published: (2025-04-01)

Can the soil seed bank of Rumex obtusifolius in productive grasslands be explained by management and soil properties?
by: Matthias Suter, et al.
Published: (2023-01-01)

Diuretic effects of hydromethanolic extract of Rumex nepalensis Spreng. leaves and its solvent fractions in mice
by: Fasika Argaw Tafesse, et al.
Published: (2025-05-01)

Effect of Cymbopogon martinii, Foeniculum vulgare, and Trachyspermum ammi Essential Oils on the Growth and Mycotoxins Production by Aspergillus Species
by: Negero Gemeda, et al.
Published: (2014-01-01)

Cluster randomized controlled trial to assess the effectiveness of a package of community-based interventions on continuum of maternal and newborn healthcare in Sidama, Ethiopia: The SiMaNeH trial protocol.
by: Achamyelesh Gebretsadik, et al.
Published: (2025-01-01)

Effects of Edible Grass (<i>Rumex patientia</i> L. × <i>Rumex tianschanicus</i> A. LOS) Leaf Powder on Growth Performance, Antioxidant Properties, Cecal Short-Chain Fatty Acids, and Microbial Community Levels in Broilers
by: Xinyao Li, et al.
Published: (2024-10-01)

Evaluation of Antioxidant, Antibacterial and Fastness Properties of Erythrina abyssinica Extracts on Cotton Fabric Using Biomordants
by: Scolastica Manyim, et al.
Published: (2025-03-01)

Temperature affects major fatty acid biosynthesis in noug (Guizotia abyssinica) self-compatible lines
by: Adane Gebeyehu, et al.
Published: (2024-12-01)

Seroprevalence of Severe Acute Respiratory Syndrome Coronavirus 2 IgG in Juba, South Sudan, 20201
by: Andrew, Baguma, et al.
Published: (2021)

Rumex japonicus Houtt. alleviates dextran sulfate sodium-induced colitis by protecting tight junctions in mice
by: Hee-Young Kim, et al.
Published: (2020-06-01)

Anchote (Coccinia abyssinica): a tuber crop with enhanced potential for innovative food products and sustainable packaging
by: Eshetie Gelagay Erku, et al.
Published: (2024-12-01)

Effect of Blend Levels on Composite Bread Prepared From Anchote (Coccinia abyssinica) Starch and Wheat Flour
by: Etalema Desta Tulu, et al.
Published: (2025-01-01)