Unleashing NK cells for cancer immunotherapy in lung cancer: biologic challenges and clinical advances

Abstract Natural killer (NK) cells are a crucial part of the innate immune system and serve as an important effector for killing tumor cells through direct cytolytic activity or immunomodulatory signaling to T cells and antigen presenting cells. NK cells are correlated with increased tumor control a...

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Bibliographic Details
Main Authors: Quinlan McLaughlin, Dorothy K. Sojka, Kathleen Kennedy, Sytse J. Piersma, Nan Sethakorn
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-025-03503-7
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