Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection.

Merkel cell polyomavirus protein ALTO modulates TBK1 activity to support persistent infection.

While Merkel cell polyomavirus (MCPyV or MCV) is an abundant virus frequently shed from healthy skin, it is one of the most lethal tumor viruses in immunocompromised individuals, highlighting the crucial role of host immunity in controlling MCPyV oncogenic potential. Despite its prevalence, very lit...

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Bibliographic Details
Main Authors: Ranran Wang, Taylor E Senay, Tiana T Luo, Wei Liu, James M Regan, Nicholas J H Salisbury, Denise A Galloway, Jianxin You
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1012170
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