Population pharmacokinetics of selexipag for dose selection and confirmation in pediatric patients with pulmonary arterial hypertension

Abstract Selexipag is an oral selective prostacyclin receptor agonist approved for the treatment of pulmonary arterial hypertension (PAH) in adults. To date, no treatment targeting the prostacyclin pathway is approved for pediatric patients. Our goal is to identify a pediatric dose regimen that resu...

Full description

Saved in:
Bibliographic Details
Main Authors: Lene Nygaard Axelsen, Anne Kümmel, Juan Jose Perez Ruixo, Alberto Russu
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:CPT: Pharmacometrics & Systems Pharmacology
Online Access:https://doi.org/10.1002/psp4.13231
Tags: Add Tag
No Tags, Be the first to tag this record!