Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis

Gut microbiota analysis and LC-MS-based metabolomics to investigate AMPK/NF-κB regulated by Clostridium butyricum in the treatment of acute pancreatitis

Abstract Background Acute pancreatitis (AP) is an inflammatory condition with potentially life-threatening complications. This study investigates the therapeutic potential of Clostridium butyricum for modulating the inflammatory cascade through the AMPK/NF-κB signaling pathway, focusing on inflammat...

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Bibliographic Details
Main Authors: Biyan Wen, Yaoxing Huang, Guiqing Deng, Qingqing Yan, Lin Jia
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
Subjects:
Acute Pancreatitis
Clostridium butyricum
AMPK/NF-κB signaling
Inflammation
Gut microbiota
LC-MS
Online Access:https://doi.org/10.1186/s12967-024-05764-w
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https://doi.org/10.1186/s12967-024-05764-w

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