Filamentation of hCTPS1 with CTP

Abstract CTP synthase (CTPS) is a key enzyme in de novo CTP synthesis, playing a critical role in nucleotide metabolism and cellular proliferation. Human CTPS1 (hCTPS1), one of the two CTPS isoforms, is essential for immune responses and is highly expressed in proliferating cells, making it a promis...

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Bibliographic Details
Main Authors: Chen-Jun Guo, Xiaojie Bao, Ji-Long Liu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-025-01450-6
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