Identification of biomarkers associated with exhausted CD8 + T cells in the tumor microenvironment of intrahepatic cholangiocarcinoma based on Mendelian randomization and bioinformatics analysis
Abstract Intrahepatic cholangiocarcinoma (iCCA) represents a growing health concern due to its increasing incidence and poor prognosis, highlighting the urgent need for biomarkers and therapeutic targets. This study utilized BayesPrism deconvolution, Weighted Gene Co-expression Network Analysis (WGC...
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| Main Authors: | LiuXing Feng, Quan Yuan, Hao Yu, RongJie Ye, ZhenHao Xie, JiaHuan Xu, XiuDong Li, ShuangJia Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer
2025-06-01
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| Series: | Discover Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.1007/s12672-025-02970-w |
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