PlsX and PlsY: Additional roles beyond glycerophospholipid synthesis in Gram-negative bacteria

ABSTRACT The unique asymmetry of the Gram-negative outer membrane, with glycerophospholipids (GPLs) in the inner leaflet and lipopolysaccharide (LPS) in the outer leaflet, works to resist external stressors and prevent the entry of toxic compounds. Thus, GPL and LPS synthesis must be tightly control...

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Bibliographic Details
Main Authors: Audrey N. Rex, Brent W. Simpson, Gregory Bokinsky, M. Stephen Trent
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
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Online Access:https://journals.asm.org/doi/10.1128/mbio.02969-24
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