SPDL1 overexpression was associated with poor prognosis and immune status in HCC through in vitro experiment and bioinformatics analysis

Abstract Background Numerous studies have established a strong link between the overexpression of spindle apparatus coiled-coil protein 1 (SPDL1) and cancer progression. However, the role of SPDL1 in hepatocellular carcinoma (HCC) remains unconfirmed. Methods The level of SPDL1 in HCC and its potent...

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Bibliographic Details
Main Authors: Ying-Ming Xu, Bo-Hua You, Ming Chen, Tian-Ping Xiong, Lin Shi, Qin Wei, Zhong-An Wang
Format: Article
Language:English
Published: Springer 2025-07-01
Series:Discover Oncology
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Online Access:https://doi.org/10.1007/s12672-025-03089-8
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