HGF Aggravated Periodontitis-Associated Gut Barrier and Microbial Dysfunction: Implications for Oral–Gut Axis Regulation

HGF Aggravated Periodontitis-Associated Gut Barrier and Microbial Dysfunction: Implications for Oral–Gut Axis Regulation

While periodontitis is increasingly linked to systemic disorders through the oral–gut axis, the molecular mediators driving gut microbiota dysbiosis and barrier disruption remain elusive. Hepatocyte growth factor (HGF), a novel regulator of inflammatory bone loss in periodontitis, may serve as a cri...

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Bibliographic Details
Main Authors: Zhen Chen, Yang Zhong, Lu Chen, Weijia Liu, Chuyin Lin, Yannan Chen, Xinhong Wang
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biology
Subjects:
periodontitis
hepatocyte growth factor
intestinal barrier
gut microbiota
oral–gut axis
Online Access:https://www.mdpi.com/2079-7737/14/5/496
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