Functional characterisation of components in two Plasmodium falciparum Cullin-RING-Ligase complexes
Abstract Ubiquitination is the key eukaryotic post-translational modification that governs protein degradation, localisation, and activity which is mediated by a concerted enzyme cascade. The largest superfamily of these enzymes include the Cullin-RING-Ligase (CRL) complexes. Plasmodium falciparum,...
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| Main Authors: | Danushka Marapana, Simon A. Cobbold, Michal Pasternak, Gerald J. Shami, Stuart A. Ralph, Sash Lopaticki, Jumana Yousef, Vineet Vaibhav, Laura F. Dagley, David Komander, Alan F. Cowman |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-05342-0 |
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