Stress granules attenuate protein nanoparticle induced osmotic imbalance via membrane potential restoration

Stress granules attenuate protein nanoparticle induced osmotic imbalance via membrane potential restoration

Abstract Stress granules (SGs) are biomolecular condensates formed in response to stress stimuli, and they can alter intracellular protein particles. Here, SG assembly was noted to effectively stabilize intermediate filament tension, intracellular osmolarity, Ca2+ signaling, and membrane potential v...

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Bibliographic Details
Main Authors: Xianrui Song, Wenzhao Zhou, Yuqing Shi, Ying Zhao, Kaili Huang, Yichen Guo, Huanhuan Zhao, Yanqiong Li, Jun Guo
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Stress granules
Protein nanoparticle–related osmotic pressure
Membrane potential
Electrochemical–tension interactions
Neuroprotection
Online Access:https://doi.org/10.1038/s41598-025-12903-w
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https://doi.org/10.1038/s41598-025-12903-w

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