Nano-encapsulated active protein AMPK inhibits cartilage matrix degradation in experimental osteoarthritis rats via SIRT1-regulated nexilin expression nano-AMPK inhibits cartilage matrix degradation

Background: Osteoarthritis (OA) is characterized by progressive cartilage matrix degradation. Although adenosine monophosphate-activated protein kinase (AMPK) shows promise in treating OA, its clinical application is limited by poor bioavailability. Nano-encapsulation may overcome this limitation, b...

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Bibliographic Details
Main Authors: X You, LQ Wu, LL Fu, QQ Wu, BR Qi
Format: Article
Language:English
Published: Forum Multimedia Publishing LLC 2025-04-01
Series:European Cells & Materials
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Online Access:https://www.ecmjournal.org/papers/vol050/vol050a07.php
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