Theaflavin-3,3'-digallate alleviates glucolipotoxicity-induced insulin secretion dysfunction in pancreatic β-TC-6 cells and zebrafish via anti-ferroptotic mechanisms by activating SERCA2
Theaflavins from black tea effectively improve insulin secretion in obesity and diabetes, but the molecular mechanisms are unclear. Here, the palmitic acid (PA)-induced pancreatic β-TC-6 cells and high fat-/high glucose-induced zebrafish were used. The effects of theaflavin-3,3’-digallate (TF3) on g...
Saved in:
| Main Authors: | Kaixi Wang, Huanqing Zhu, Jiaxin Kang, Shuna Chen, Puming He, Youying Tu, Bo Li |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Tsinghua University Press
2025-04-01
|
| Series: | Food Science and Human Wellness |
| Subjects: | |
| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2024.9250096 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Different Proteostasis Mechanisms Facilitate the Assembly of Individual Components on the Chitin Synthase 3 Complex at the Endoplasmic Reticulum
by: Noelia Sánchez, et al.
Published: (2025-03-01) -
Thiram-induced ER stress promotes mitochondrial calcium signaling and NLRP3 inflammasome activation in a tissue specific manner
by: Shah Nawaz, et al.
Published: (2025-03-01) -
USP18 attenuates endoplasmic reticulum stress via the PERK-eIF2α-ATF4 axis to reduce apoptosis in hepatocellular carcinoma cells
by: Lin Li, et al.
Published: (2025-05-01) -
Endoplasmic reticulum stress contributes to insulin resistance in Hashimoto’s thyroiditis
by: Qing Zhou, et al.
Published: (2025-08-01) -
NR4A3 regulates anoikis resistance and metastasis of bladder cancer through EWSR1
by: Li Fan, et al.
Published: (2025-12-01)