Natural killer cell granule protein 7 contributes to CD8+ T cell-mediated platelet apoptosis in immune thrombocytopenia

Natural killer cell granule protein 7 contributes to CD8+ T cell-mediated platelet apoptosis in immune thrombocytopenia

Background: CD8+ T cells participate in the pathogenesis of primary immune thrombocytopenia (ITP). Natural killer cell granule protein 7 (NKG7) is essential for natural killer cell and CD8+ T cell cytotoxicity. The function of NKG7 in CD8+ T cells in ITP remains unclear. Objectives: We investigated...

Full description

Saved in:
Bibliographic Details
Main Authors: Xiaolin Wang, Qiang Liu, Xiaojing Li, Wei Xing, Ping Chen, Qi Feng, Ming Hou, Qian Wang, Hai Zhou, Jun Peng
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
blood platelets
CD8-positive T lymphocytes
cytotoxicity immunologic
NKG7 protein, human
purpura, thrombocytopenic, idiopathic
Online Access:http://www.sciencedirect.com/science/article/pii/S2475037925003012
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S2475037925003012

Similar Items