Bigel formulations of St. John’s wort extract in wound healing: toxicological aspects

Bigel formulations of St. John’s wort extract in wound healing: toxicological aspects

This study aimed to investigate the toxicological profile of hyperforin (HP) in silico and to assess it in vivo after topical application of an HP-rich St. John’s wort (SJW) extract. The former analysis predicted low toxicity because of HP’s inability to bind DNA or proteins, but structural alerts f...

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Bibliographic Details
Main Authors: Yoana Sotirova, Deyana Vankova, Oskan Tasinov, Stefka Stoeva, Minka Hristova, Ivelin Iliev, Svetlana Georgieva, Yoana Kiselova-Kaneva, Velichka Andonova
Format: Article
Language:English
Published: Taylor & Francis Group 2023-03-01
Series:Biotechnology & Biotechnological Equipment
Subjects:
Bigels
hyperforin
QSAR
Hypericum perforatum
in vivo toxicity
wounds
Online Access:https://www.tandfonline.com/doi/10.1080/13102818.2023.2263570
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https://www.tandfonline.com/doi/10.1080/13102818.2023.2263570

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