Cell cycle-dependent TICRR/TRESLIN and MTBP chromatin binding mechanisms and patterns
Abstract Background The selection of replication origins is a defining characteristic of DNA replication in eukaryotes, yet its mechanism in humans has not been well defined. Potential DNA replication origins are licensed through the recruitment of a pair of minichromosome maintenance complexes (MCM...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-07-01
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| Series: | Genome Biology |
| Online Access: | https://doi.org/10.1186/s13059-025-03665-9 |
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