Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes
<b>Aim:</b> The primary aim of this study was to evaluate the changes in hematological and certain biochemical parameters in the diagnosis of rabbits with experimental diabetes mellitus induced with two different doses of alloxan monohydrate (100 and 175 mg/kg). The secondary aim of this...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Selcuk University Press
|
| Series: | Eurasian Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=541 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841561499953266688 |
|---|---|
| author | Bahadır Ersan Mahmut Ok |
| author_facet | Bahadır Ersan Mahmut Ok |
| author_sort | Bahadır Ersan |
| collection | DOAJ |
| description | <b>Aim:</b> The primary aim of this study was to evaluate the
changes in hematological and certain biochemical parameters
in the diagnosis of rabbits with experimental diabetes
mellitus induced with two different doses of alloxan monohydrate
(100 and 175 mg/kg). The secondary aim of this
study was to determine the importance of glucose, haemoglobin
A1c and fructosamine in the diagnosis of the disease.<p>
<b>Materials and Methods:</b> Rabbits were randomly allocated
to two groups. The first group included 12 rabbits and the
second group included 13 rabbits. Hundred and 175 mg/
kg dose of the alloxan solutions were given intravenously to
the first group and second group, respectively. White blood
cell, red blood cell, haemoglobin, platelet counts, paced cell
volume, mean corpuscular haemoglobin concentration and
mean corpuscular volume values were determined. Fasting
serum glucose, fructosamine, insulin, haemoglobin HbA1c,
total cholesterol, triglyceride, urea, aspartate amino transferase
and alanin amino transferase levels were measured.<p>
<b>Results:</b> Statistically significantly increases of serum fasting
glucose, fructosamine, haemoglobin A1c, total cholesterol
and triglyceride concentrations and decreases of
serum insulin levels and red blood cell, paced cell volume
and haemoglobin values were determined (p<0.05) in both
groups.<p>
<b>Conclusion:</b> Fasting serum glucose, fructosamine and haemoglobin
A1c could be more important indicators for the
diagnosis of diabetes mellitus. |
| format | Article |
| id | doaj-art-8cd7fcc1a7e34c228dc8a86f9ca5c170 |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-8cd7fcc1a7e34c228dc8a86f9ca5c1702025-01-03T01:36:14ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-19532711318541Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetesBahadır ErsanMahmut Ok<b>Aim:</b> The primary aim of this study was to evaluate the changes in hematological and certain biochemical parameters in the diagnosis of rabbits with experimental diabetes mellitus induced with two different doses of alloxan monohydrate (100 and 175 mg/kg). The secondary aim of this study was to determine the importance of glucose, haemoglobin A1c and fructosamine in the diagnosis of the disease.<p> <b>Materials and Methods:</b> Rabbits were randomly allocated to two groups. The first group included 12 rabbits and the second group included 13 rabbits. Hundred and 175 mg/ kg dose of the alloxan solutions were given intravenously to the first group and second group, respectively. White blood cell, red blood cell, haemoglobin, platelet counts, paced cell volume, mean corpuscular haemoglobin concentration and mean corpuscular volume values were determined. Fasting serum glucose, fructosamine, insulin, haemoglobin HbA1c, total cholesterol, triglyceride, urea, aspartate amino transferase and alanin amino transferase levels were measured.<p> <b>Results:</b> Statistically significantly increases of serum fasting glucose, fructosamine, haemoglobin A1c, total cholesterol and triglyceride concentrations and decreases of serum insulin levels and red blood cell, paced cell volume and haemoglobin values were determined (p<0.05) in both groups.<p> <b>Conclusion:</b> Fasting serum glucose, fructosamine and haemoglobin A1c could be more important indicators for the diagnosis of diabetes mellitus.http://eurasianjvetsci.org/pdf.php3?id=541alloxandiabetes mellitushaemoglobin a1cfructosamine |
| spellingShingle | Bahadır Ersan Mahmut Ok Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes Eurasian Journal of Veterinary Sciences alloxan diabetes mellitus haemoglobin a1c fructosamine |
| title | Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes |
| title_full | Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes |
| title_fullStr | Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes |
| title_full_unstemmed | Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes |
| title_short | Importance of fasting serum glucose, haemoglobin a1c and fructosamine in the diagnosis of diabetes |
| title_sort | importance of fasting serum glucose haemoglobin a1c and fructosamine in the diagnosis of diabetes |
| topic | alloxan diabetes mellitus haemoglobin a1c fructosamine |
| url | http://eurasianjvetsci.org/pdf.php3?id=541 |
| work_keys_str_mv | AT bahadırersan importanceoffastingserumglucosehaemoglobina1candfructosamineinthediagnosisofdiabetes AT mahmutok importanceoffastingserumglucosehaemoglobina1candfructosamineinthediagnosisofdiabetes |