Contribution of IL-17C-mediated macrophage polarization to Type 17 inflammation in neutrophilic asthma

Contribution of IL-17C-mediated macrophage polarization to Type 17 inflammation in neutrophilic asthma

Abstract Background IL-17C has been described in a variety of inflammatory diseases driven by neutrophils. However, the role of IL-17C in neutrophilic asthma has not been completely characterized. Methods The level of IL-17C in asthmatic patients and mice was assessed. Il-17c-deficient mice or mice...

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Main Authors: Yuhuan Wen, Qile Chen, Hao Wang, Shiyun Xie, Honglv Chen, Wenruo Yao, Le Zhang, Weimin Sun, Junjie Wen, Xiaojing Yang, Kian Fan Chung, Qingling Zhang, Ailin Tao, Jie Yan
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cell Communication and Signaling
Subjects:
Asthma
IL-17C
IL-17RE
Macrophages
Online Access:https://doi.org/10.1186/s12964-024-01937-8
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https://doi.org/10.1186/s12964-024-01937-8

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