Zhishi Xiebai Guizhi Decoction modulates hypoxia and lipid toxicity to alleviate pulmonary vascular remodeling of pulmonary hypertension in rats

Zhishi Xiebai Guizhi Decoction modulates hypoxia and lipid toxicity to alleviate pulmonary vascular remodeling of pulmonary hypertension in rats

Abstract Background Pulmonary hypertension (PH) is a severe cardio-pulmonary vascular disease, involves complex molecular mechanism especially during the pathological process of pulmonary vascular remodeling, brings a significant challenge to clinical treatment and thus resulting in high mortality r...

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Bibliographic Details
Main Authors: Min Fu, Yuan Li, Jingjing Liu, Junjie Liu, Jiaoxia Wei, Yuxin Qiao, Hanxin Zhong, Dongyang Han, Haitao Lu, Li Yao
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Chinese Medicine
Subjects:
Zhishi Xiebai Guizhi Decoction
Pulmonary hypertension
Pulmonary vascular remodeling
Chemical compounds
HIF-1α
Online Access:https://doi.org/10.1186/s13020-024-01039-0
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https://doi.org/10.1186/s13020-024-01039-0

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