Effects of Different Concentrations of AmB on the Unsaturated Phospholipid–Cholesterol Membrane Using the Langmuir Monolayer and Liposome Models

Amphotericin B (AmB) causes toxicity to the erythrocyte membrane, leading to hemolysis, which limits the clinically effective dose for AmB intravenous therapy in invasive fungal infections. The molecular mechanism by which AmB adheres to the membrane of erythrocytes is the key factor in causing AmB...

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Bibliographic Details
Main Authors: Juan Wang, Jia Wang, Mingyue Zheng, Da Li
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/23/5659
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