A yeast one‐hybrid and microfluidics‐based pipeline to map mammalian gene regulatory networks

A yeast one‐hybrid and microfluidics‐based pipeline to map mammalian gene regulatory networks

Abstract The comprehensive mapping of gene promoters and enhancers has significantly improved our understanding of how the mammalian regulatory genome is organized. An important challenge is to elucidate how these regulatory elements contribute to gene expression by identifying their trans‐regulator...

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Main Authors: Carine Gubelmann, Sebastian M Waszak, Alina Isakova, Wiebke Holcombe, Korneel Hens, Antonina Iagovitina, Jean‐Daniel Feuz, Sunil K Raghav, Jovan Simicevic, Bart Deplancke
Format: Article
Language:English
Published: Springer Nature 2013-08-01
Series:Molecular Systems Biology
Subjects:
gene regulatory networks
microfluidics
mouse open‐reading frame (ORF) clone collection
transcription factor
yeast one‐hybrid
Online Access:https://doi.org/10.1038/msb.2013.38
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https://doi.org/10.1038/msb.2013.38

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