Exploring the therapeutic potential of triterpenoid saponins from Gymnema sylvestre: Mechanistic insights into hepatoprotection, immunomodulation, anticancer activities, molecular docking, and pharmacokinetics

Exploring the therapeutic potential of triterpenoid saponins from Gymnema sylvestre: Mechanistic insights into hepatoprotection, immunomodulation, anticancer activities, molecular docking, and pharmacokinetics

The study comprehensively investigated the therapeutic potential of Gymnema sylvestre triterpenoid saponin extract (GST), encompassing its hepatoprotective, immunomodulatory, and anticancer activities. The study employed a Prednisolone (PRD)-induced immunosuppressed rat model to assess the hepatopro...

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Bibliographic Details
Main Authors: Vasudeva Reddy Netala, Tianyu Hou, Rajakumari Devarapogu, Murali Satyanarayana Bethu, Zhijun Zhang, Tartte Vijaya
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Heliyon
Subjects:
Gymnema sylvestre
Triterpenoid saponin extract
Hepatoprotective
Antioxidant
Immunomodulatory
Anticancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024168818
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http://www.sciencedirect.com/science/article/pii/S2405844024168818

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