Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1

Abstract Background Ficolins were originally identified as proteins that bind to transforming growth factor-β1 (TGF-β1). They are capable of activating the complement system through lectin pathway for immune system protection. Ficolin-2 and 3 have been identified in patients with interstitial lung d...

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Bibliographic Details
Main Authors: Pengfei Gao, Yanjiao Lu, Kun Tang, Wei Wang, Tongsheng Wang, Yingwei Zhu, Jianping Zhao, Yimin Mao
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Translational Medicine
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Online Access:https://doi.org/10.1186/s12967-024-05894-1
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