Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1
Abstract Background Ficolins were originally identified as proteins that bind to transforming growth factor-β1 (TGF-β1). They are capable of activating the complement system through lectin pathway for immune system protection. Ficolin-2 and 3 have been identified in patients with interstitial lung d...
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Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-11-01
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Series: | Journal of Translational Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12967-024-05894-1 |
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