Auxilin in enterocytes controls intestinal homeostasis through inter-cell communication

Abstract Residential stem cells sense extrinsic and intrinsic signals to proliferate accordingly to maintain homeostasis. However, how differentiated cells control stem cell proliferation still remains elusive. Here, we find that Auxilin (Aux) maintains enterocyte (EC) integrity to prevent unlimited...

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Bibliographic Details
Main Authors: Runqi Wang, Zhengran Li, Jing Wei, Ruiyan Kong, Xuejing Ren, Hang Zhao, Danjie Zhang, Xiyue Tao Liu, Zhouhua Li
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07954-w
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