Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

Defining the cellular factors that drive growth rate and proteome composition is essential for understanding and manipulating cellular systems. In bacteria, ribosome concentration is known to be a constraining factor of cell growth rate, while gene concentration is usually assumed not to be limiting...

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Bibliographic Details
Main Authors: Jarno Mäkelä, Alexandros Papagiannakis, Wei-Hsiang Lin, Michael Charles Lanz, Skye Glenn, Matthew Swaffer, Georgi K Marinov, Jan M Skotheim, Christine Jacobs-Wagner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-12-01
Series:eLife
Subjects:
Caulobacter crescentus
ribosomes
cell growth
transcription
limitation
proteome allocation
Online Access:https://elifesciences.org/articles/97465
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https://elifesciences.org/articles/97465

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