Dual risk of anticholinergic burden and CSF alzheimer’s biomarkers in older patients: a mortality follow-up study from daily medical practice

Dual risk of anticholinergic burden and CSF alzheimer’s biomarkers in older patients: a mortality follow-up study from daily medical practice

Abstract Background Anticholinergic medications are widely prescribed to older adults and are linked to increased mortality and cognitive decline. Cerebrospinal fluid (CSF) biomarkers of Alzheimer’s disease (AD)—amyloid and tau—are strong prognostic indicators in neurocognitive disorders (NCD). Howe...

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Bibliographic Details
Main Authors: Théodore Decaix, Julien Dumurgier, Emmanuel Cognat, Karl Götze, François Mouton-Liger, Jacques Hugon, Elodie Bouaziz-Amar, Matthieu Lilamand, Claire Paquet
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Alzheimer’s Research & Therapy
Subjects:
Anticholinergic medication
Cognition
Dementia
Older adult
Clinical practice
Online Access:https://doi.org/10.1186/s13195-025-01814-7
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https://doi.org/10.1186/s13195-025-01814-7

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