Integrating Circle-Seq with transcriptomics reveals genome-wide characterization of extrachromosomal circular DNA for dilated cardiomyopathy
Abstract Background Extrachromosomal circular DNAs (eccDNAs) are commonly found in various tumors and play a critical role in promoting oncogenesis. However, little is known about the characteristics and nature of eccDNAs in human heart failure. The aim of this study was to comprehensively analyze e...
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Main Authors: | Zhenhao Lin, Fangjie Dai, Bo Li, Yongchao Zhao, Changqian Wang |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-11-01
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Series: | Biology Direct |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13062-024-00556-0 |
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