Integrating Circle-Seq with transcriptomics reveals genome-wide characterization of extrachromosomal circular DNA for dilated cardiomyopathy

Abstract Background Extrachromosomal circular DNAs (eccDNAs) are commonly found in various tumors and play a critical role in promoting oncogenesis. However, little is known about the characteristics and nature of eccDNAs in human heart failure. The aim of this study was to comprehensively analyze e...

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Bibliographic Details
Main Authors: Zhenhao Lin, Fangjie Dai, Bo Li, Yongchao Zhao, Changqian Wang
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Biology Direct
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Online Access:https://doi.org/10.1186/s13062-024-00556-0
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