A case report on weak subgroup of A: Aend

A end is a weak subgroup of Blood group A, found rarely in general population, not detected by routine forward and reverse blood grouping, detected by Adsorption/Elution technique along with saliva testing for A, B and H antigens. Although it is subgroup of A but it lacks A antigen in saliva and con...

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Main Authors: Saurabh Lahare, Ramesh Chandrakar, Minal Wasnik
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Asian Journal of Transfusion Science
Subjects:
Online Access:https://journals.lww.com/10.4103/ajts.AJTS_37_19
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author Saurabh Lahare
Ramesh Chandrakar
Minal Wasnik
author_facet Saurabh Lahare
Ramesh Chandrakar
Minal Wasnik
author_sort Saurabh Lahare
collection DOAJ
description A end is a weak subgroup of Blood group A, found rarely in general population, not detected by routine forward and reverse blood grouping, detected by Adsorption/Elution technique along with saliva testing for A, B and H antigens. Although it is subgroup of A but it lacks A antigen in saliva and contains only H antigen. A 25y/M was accepted for blood donation and showed weak/mf reaction with anti-A in forward grouping. On Adsorption/Elution testing eluate gave 2+ reaction with known A1 cells, and Saliva testing showed presence of only H substance. A weak A can be mistyped as O & can lead to a Hemolytic transfusion reaction so anti-H, anti-A1 & anti-AB should be incorporated in forward grouping and every O group sample should be treated with anti-AB antisera.
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institution Kabale University
issn 0973-6247
1998-3565
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Asian Journal of Transfusion Science
spelling doaj-art-88dba9d6978048c89d0324b8a8fba54d2025-01-08T09:10:45ZengWolters Kluwer Medknow PublicationsAsian Journal of Transfusion Science0973-62471998-35652024-12-0118233033210.4103/ajts.AJTS_37_19A case report on weak subgroup of A: AendSaurabh LahareRamesh ChandrakarMinal WasnikA end is a weak subgroup of Blood group A, found rarely in general population, not detected by routine forward and reverse blood grouping, detected by Adsorption/Elution technique along with saliva testing for A, B and H antigens. Although it is subgroup of A but it lacks A antigen in saliva and contains only H antigen. A 25y/M was accepted for blood donation and showed weak/mf reaction with anti-A in forward grouping. On Adsorption/Elution testing eluate gave 2+ reaction with known A1 cells, and Saliva testing showed presence of only H substance. A weak A can be mistyped as O & can lead to a Hemolytic transfusion reaction so anti-H, anti-A1 & anti-AB should be incorporated in forward grouping and every O group sample should be treated with anti-AB antisera.https://journals.lww.com/10.4103/ajts.AJTS_37_19a subgroupaendblood group aweak asaliva testing
spellingShingle Saurabh Lahare
Ramesh Chandrakar
Minal Wasnik
A case report on weak subgroup of A: Aend
Asian Journal of Transfusion Science
a subgroup
aend
blood group a
weak a
saliva testing
title A case report on weak subgroup of A: Aend
title_full A case report on weak subgroup of A: Aend
title_fullStr A case report on weak subgroup of A: Aend
title_full_unstemmed A case report on weak subgroup of A: Aend
title_short A case report on weak subgroup of A: Aend
title_sort case report on weak subgroup of a aend
topic a subgroup
aend
blood group a
weak a
saliva testing
url https://journals.lww.com/10.4103/ajts.AJTS_37_19
work_keys_str_mv AT saurabhlahare acasereportonweaksubgroupofaaend
AT rameshchandrakar acasereportonweaksubgroupofaaend
AT minalwasnik acasereportonweaksubgroupofaaend
AT saurabhlahare casereportonweaksubgroupofaaend
AT rameshchandrakar casereportonweaksubgroupofaaend
AT minalwasnik casereportonweaksubgroupofaaend