A case report on weak subgroup of A: Aend
A end is a weak subgroup of Blood group A, found rarely in general population, not detected by routine forward and reverse blood grouping, detected by Adsorption/Elution technique along with saliva testing for A, B and H antigens. Although it is subgroup of A but it lacks A antigen in saliva and con...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | Asian Journal of Transfusion Science |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/ajts.AJTS_37_19 |
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| Summary: | A end is a weak subgroup of Blood group A, found rarely in general population, not detected by routine forward and reverse blood grouping, detected by Adsorption/Elution technique along with saliva testing for A, B and H antigens. Although it is subgroup of A but it lacks A antigen in saliva and contains only H antigen. A 25y/M was accepted for blood donation and showed weak/mf reaction with anti-A in forward grouping. On Adsorption/Elution testing eluate gave 2+ reaction with known A1 cells, and Saliva testing showed presence of only H substance. A weak A can be mistyped as O & can lead to a Hemolytic transfusion reaction so anti-H, anti-A1 & anti-AB should be incorporated in forward grouping and every O group sample should be treated with anti-AB antisera. |
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| ISSN: | 0973-6247 1998-3565 |