Regenerative Outcomes of Combining siCOL1A2 Hydrogel with Acupuncture in a Rat Model of Chronic Intervertebral Disc Degeneration

Regenerative Outcomes of Combining siCOL1A2 Hydrogel with Acupuncture in a Rat Model of Chronic Intervertebral Disc Degeneration

Intervertebral disc degeneration (IVDD) is a significant cause of chronic pain and disability, necessitating innovative therapeutic strategies. This study investigates the combined effect of a novel siCOL1A2-encapsulated hydrogel and acupuncture on IVDD in a rat model. We developed a hydrogel system...

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Bibliographic Details
Main Authors: Qianfu Zhang, Zhixuan Li, Sihan Zhou, Ji Li
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Bioengineering
Subjects:
intervertebral disc degeneration
cryogel
inflammation
siCOL1A2
acupuncture
chronic pain
Online Access:https://www.mdpi.com/2306-5354/11/11/1066
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https://www.mdpi.com/2306-5354/11/11/1066

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