Radotinib inhibits mitosis entry in acute myeloid leukemia cells via suppression of Aurora kinase A expression
Aurora kinases play critical roles in regulating several processes pivotal for mitosis. Radotinib, which is approved in South Korea as a second-line treatment for chronic myeloid leukemia, inhibits the tyrosine kinase BCR-ABL and platelet-derived growth factor receptor. However, the effects of radot...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2019-05-01
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| Series: | Tumor Biology |
| Online Access: | https://doi.org/10.1177/1010428319848612 |
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