Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells

Antagonistic anti-LILRB1 monoclonal antibody regulates antitumor functions of natural killer cells

Background Current immune checkpoint blockade strategies have been successful in treating certain types of solid cancer. However, checkpoint blockade monotherapies have not been successful against most hematological malignancies including multiple myeloma and leukemia. There is an urgent need to ide...

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Main Authors: Ningshao Xia, Weina Chen, Hisashi Arase, Hai Yu, Xiaoye Liu, Heyu Chen, Ningyan Zhang, Zhiqiang An, Cheng Cheng Zhang, Yang Huang, Jingjing Xie, Xun Gui, Wenxin Luo, Guojin Wu, Yuanzhi Chen, Mi Deng, Samuel John, Ankit Kansagra, Jaehyup Kim, Cheryl Lewis, Lingbo Zhang, Ryan Huang
Format: Article
Language:English
Published: BMJ Publishing Group 2020-10-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/8/2/e000515.full
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https://jitc.bmj.com/content/8/2/e000515.full

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