IRF2BP2 binds to a conserved RxSVI motif of protein partners and regulates megakaryocytic differentiation

Abstract IRF2BP2 is a transcriptional coregulator that plays diverse regulatory roles in various cellular processes in either IRF2-dependent or IRF2-independent manner through interactions with protein partners via its RING domain; however, the underlying molecular mechanisms remain unclear. In this...

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Bibliographic Details
Main Authors: Guanchao Wang, Tiantian Lu, Lei Zhang, Jianping Ding
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54889-5
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