A mechanistic computational model of HGF-VEGF-mediated endothelial cell proliferation and vascular permeability

Summary: Hepatocyte growth factor (HGF) and vascular endothelial growth factor (VEGF) are important pro-angiogenic factors in angiogenesis-dependent diseases. While sharing some signaling pathways, their contrasting effect on vascular permeability remains under investigation. To explore how these fa...

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Bibliographic Details
Main Authors: Rebeca Hannah de Melo Oliveira, Akash Patil, Brian H. Annex, Arvind P. Pathak, Aleksander S. Popel
Format: Article
Language:English
Published: Elsevier 2025-08-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225014609
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