It takes two to tango: Preserving daptomycin efficacy against daptomycin-resistant MRSA using daptomycin-phage co-therapy

It takes two to tango: Preserving daptomycin efficacy against daptomycin-resistant MRSA using daptomycin-phage co-therapy

ABSTRACT Daptomycin (DAP) is a cyclic lipopeptide antibiotic that targets the cell membrane and is commonly used for the treatment of multidrug-resistant Staphylococcus aureus infections, especially methicillin-resistant strains (MRSA). Emergence of DAP resistance during DAP therapy is increasingly...

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Bibliographic Details
Main Authors: Casey L. Madison, Anja S. J. Steinert, Corrin E. Luedeke, Neeka Hajjafar, Prakhar Srivastava, Andrew D. Berti, Arnold S. Bayer, Razieh Kebriaei
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:Microbiology Spectrum
Subjects:
antibiotic resistance
bacteriophage therapy
Staphylococcus aureus
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00679-24
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https://journals.asm.org/doi/10.1128/spectrum.00679-24

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