Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit

Control of spatio-temporal patterning via cell growth in a multicellular synthetic gene circuit

Abstract A major goal in synthetic development is to build gene regulatory circuits that control patterning. In natural development, an interplay between mechanical and chemical communication shapes the dynamics of multicellular gene regulatory circuits. For synthetic circuits, how non-genetic prope...

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Main Authors: Marco Santorelli, Pranav S. Bhamidipati, Josquin Courte, Benjamin Swedlund, Naisargee Jain, Kyle Poon, Dominik Schildknecht, Andriu Kavanagh, Victoria A. MacKrell, Trusha Sondkar, Mattias Malaguti, Giorgia Quadrato, Sally Lowell, Matt Thomson, Leonardo Morsut
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-53078-8
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https://doi.org/10.1038/s41467-024-53078-8

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