Role of periodontal ligament fibroblasts in periodontitis: pathological mechanisms and therapeutic potential

Role of periodontal ligament fibroblasts in periodontitis: pathological mechanisms and therapeutic potential

Abstract Periodontal ligament fibroblasts (PDLFs) play a crucial role in the etiology of periodontitis and periodontal tissue regeneration. In healthy periodontal tissues, PDLFs maintain the homeostasis of periodontal soft and hard tissues as well as the local immune microenvironment. PDLFs also hav...

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Bibliographic Details
Main Authors: Yijie Huang, Ying Tang, Ruiqi Zhang, Xiao Wu, Li Yan, Xiling Chen, Qianqi Wu, Yiyan Chen, Yingtao Lv, Yuan Su
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Translational Medicine
Subjects:
Periodontal Ligament Fibroblasts
Periodontitis
Pathological Mechanisms
Regeneration of periodontal tissue
Online Access:https://doi.org/10.1186/s12967-024-05944-8
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