Serum IgA/C3 ratio as a diagnostic and prognostic biomarker for IgA nephropathy

Serum IgA/C3 ratio as a diagnostic and prognostic biomarker for IgA nephropathy

Abstract IgA nephropathy (IgAN) is a common glomerular disease in adults with a smoldering course and high risk of progression to end-stage kidney disease (ESKD) in South Asians. We investigated serum IgA/C3 ratio as a potential biomarker for IgAN. We measured serum levels of IgA and C3 in 258 patie...

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Main Authors: Anitha Swamy, Abin Antony, Sudip Kumar Datta, Kalaivani Mani, Adarsh Barwad, Geetika Singh, Arunkumar Subbiah, Raj Kanwar Yadav, Sandeep Mahajan, Dipankar Bhowmik, Sanjay Kumar Agarwal, Soumita Bagchi
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
IgA nephropathy
IgA/C3 ratio
Biomarker
Outcome
Online Access:https://doi.org/10.1038/s41598-025-10578-x
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