Automated in-situ monitoring of accelerated crystallization processes of nifedipine using terahertz time-domain spectroscopy

Automated in-situ monitoring of accelerated crystallization processes of nifedipine using terahertz time-domain spectroscopy

Abstract We developed and tested an automated measurement platform which can fit multiple samples for their investigation in transmission mode using terahertz time-domain spectroscopy. The temperature inside the platform can be varied to simulate different storage conditions of the samples, in our c...

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Bibliographic Details
Main Authors: Lara Heidrich, Julian Wiener, Enrique Castro-Camus, Martin Koch, Jan Ornik
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Terahertz spectroscopy
Automatization
Quality control
Crystallinity
Pharmaceuticals
Online Access:https://doi.org/10.1038/s41598-024-81316-y
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https://doi.org/10.1038/s41598-024-81316-y

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