RNAseq and targeted metabolomics implicate RIC8 in regulation of energy homeostasis, amino acid compartmentation, and asexual development in Neurospora crassa

RNAseq and targeted metabolomics implicate RIC8 in regulation of energy homeostasis, amino acid compartmentation, and asexual development in Neurospora crassa

ABSTRACT Heterotrimeric G protein signaling pathways control growth and development in eukaryotes. In the multicellular fungus Neurospora crassa, the guanine nucleotide exchange factor RIC8 regulates heterotrimeric Gα subunits. In this study, we used RNAseq and liquid chromatography-mass spectrometr...

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Bibliographic Details
Main Authors: Monique Quinn, Alexander J. Carrillo, Lida Halilovic, Katherine A. Borkovich
Format: Article
Language:English
Published: American Society for Microbiology 2024-12-01
Series:mBio
Subjects:
heterotrimeric G proteins
nonreceptor guanine nucleotide exchange factor
filamentous fungi
asexual development
amino acid compartmentation
arginine
Online Access:https://journals.asm.org/doi/10.1128/mbio.03133-24
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https://journals.asm.org/doi/10.1128/mbio.03133-24

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